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Updated: Jul 11, 2026

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在急性损伤治疗中MSCs:通过PGC-1α调节线粒体功能并通过PGC-1α抑制 Pyroptosis

Yanjun Wang1, Yanlin Ding2, Haiyun Dong2

  • 1Department of Nephrology, Affiliated Hospital of Qinghai University, Xining, Qinghai 810001,China; Research Center for High Altitude Medicine, Qinghai University, Xining, Qinghai 810016,China; High-Altitude Medicine Key Laboratory of the Ministry of Educationy, Xining, Qinghai 810001,China; Qinghai Provincial Key Laboratory for Application of High-Altitude Medicine (Qinghai-Utah Joint Key Laboratory for Plateau Medicine), Xining, Qinghai 810001,China.

Experimental cell research
|May 5, 2025
PubMed
概括

介质干细胞 (MSCs) 通过改善线粒体功能和抑制管状上皮细胞 (RTECs) 中的热亡,增强急性损伤的修复. 这种疗法可以长期保护纤维化.

关键词:
急性脏损伤 严重的脏损伤慢性脏疾病 慢性脏疾病介质细胞干细胞 介质细胞干细胞线粒体动力学的动力学它们是PGC-1α.

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