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Updated: May 9, 2025

Tools to Study the Role of Architectural Protein HMGB1 in the Processing of Helix Distorting, Site-specific DNA Interstrand Crosslinks
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Published on: November 10, 2016

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靠近紫外线和可见光诱导的IgG1基模式的特定部位碎片化,由histidine和Fe(III介导):对于域内相互作用的作用?

Maribel Espinoza Ballesteros1, Thomas Tolbert1, Christian Schöneich1

  • 1Department of Pharmaceutical Chemistry, University of Kansas, 2093 Constant Avenue, Lawrence, KS 66047, USA.

Journal of pharmaceutical sciences
|May 5, 2025
PubMed
概括

蛋白质的光稳定性对于治疗开发至关重要. 基于IgG1的模式的差异,如HM-Fc,NISTmAb和Flt-3L-Ig,影响光诱导的碎片化,受糖化和域相互作用等因素的影响.

关键词:
在Fc融合蛋白质中.希斯蒂丁因 (Histidine) 是一种氨酸.碎片可以结晶,可结晶.碎片化的碎片化 碎片化的碎片化在紫外线附近的紫外线.氧化过程中的氧化.照片降解的降解可见光 可见光 可见光.

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