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Updated: May 12, 2025

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使用结合PK-PD建模对协同效应的机制性见解

Jinzhou Sun1, Qianqian Chen2, Chumeng Zhuang2

  • 1School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, 310053, China.

Scientific reports
|May 5, 2025
PubMed
概括

水氧沙夫黄A (HSYA) 和卡利科辛 (CA) 在治疗缺血性中风方面表现出协同作用. 一种新的PK-PD结合模型量化了这种协同作用,揭示了药物代谢的增强和治疗益处.

关键词:
卡利科辛 (Calycosin) 是一种有氧化物.与PK-PD相结合的PK-PD相结合氧黄 A 黄色 A 黄色有协同效应的效应.

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