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在接受化疗的老年癌症患者中,脆弱性和口味变化之间的关联
Yajun Dong1, Jiajia Lu2, Danhui Wang1
1Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Cancer investigation
|May 6, 2025
概括
味觉的变化,如phantogeusia和parageusia,显著增加了接受化疗的老年癌症患者的脆弱性. 这突显了口味变化是影响癌症治疗期间患者脆弱性的关键因素.
科学领域:
- 老年学是指老年学的学科.
- 在瘤学瘤学.
- 感官科学 感官科学
背景情况:
- 化疗经常导致味道变化,影响老年癌症患者的生活质量.
- 对老年人来说,脆弱性是一个关键问题,尤其是那些接受癌症治疗的人.
- 化疗引起的味道变化与患者脆弱性之间的关系需要进一步研究.
研究的目的:
- 研究接受化疗的老年癌症患者的味道变化和脆弱性之间的关联.
- 为了确定与该群体的脆弱性增加相关的特定味道变化.
主要方法:
- 一项涉及200名在中国无锡接受化疗的老年癌症患者的横截面研究.
- 使用化疗诱导的味道变化量表 (CiTAS) 来评估味道变化.
- 使用易受伤害的老年人调查 (VES) 来确定脆弱状态.
- 统计分析包括单变量,相关性和等级回归.
主要成果:
- 在口味变化水平和脆弱性之间发现了正相关性 (r=0.401,p<0.01).
- 脆弱性与经历phantogeusia和parageusia的更高几率显著相关 (OR=4.505,p<0.001).
- 单变量分析显示了基于教育,气味异常,饮酒史和化疗周期的脆弱性差异.
结论:
- 味觉变化,特别是phantogeusia和parageusia,是影响老年癌症患者易受伤害的重要因素.
- 监测和管理味道变化可能对于解决这个患者群体的脆弱性至关重要.
- 需要进一步的研究来探索针对味道变化的干预措施,以减轻脆弱性.
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