神经发育和与中度和晚期早产婴儿早期生活营养的关联
Anne H Lafeber1, Mark Bosch1, Sophie F de Roos1
1Department of Pediatrics and Neonatology, North West Clinics, Alkmaar, the Netherlands.
概括
中度和晚期早产婴儿 (MLPTI) 的神经发育在两岁的校正年龄是正常的,但男孩的得分低于女孩. 早期营养没有影响这些婴儿以后的神经发育结果.
科学领域:
- 新生儿研究新生儿研究
- 发育儿科 发育儿科
- 营养科学 营养科学
背景情况:
- 适度及晚期早产婴儿 (MLPTI) 的神经发育结果较为低,相比于按时出生的婴儿.
- 早期的营养摄入,特别是蛋白质和能量,与非常早产婴儿早期神经发育的改善有关.
研究的目的:
- 评估MLPTI在2年校正年龄 (CA) 的神经发育结果.
- 在MLPTI中调查生命第一周营养摄入量与神经发育结果在2年CA之间的关联.
主要方法:
- 在生命的第一个星期从100个MLPTI (GA 32-35周) 收集营养数据.
- 在使用贝利婴儿和幼儿发展尺度的2年CA神经发育评估,第三版 (BSID-III-NL).
主要成果:
- 认知 (103.1 ± 10.9),语言 (101.1 ± 15.0) 和运动 (100.8 ± 9.6) 复合物的平均BSID-III-NL得分处于正常范围内.
- 与女孩相比,男孩的认知和语言综合分数明显较低.
- 在CA2年后,第一周营养摄入量和神经发育结果之间没有发现显著的关联.
结论:
- 在2年CA的MLPTI中神经发育通常在正常范围内,男孩的得分比女孩低.
- 生命的第一个星期的营养摄入量似乎不会影响2岁CA的神经发育结果.
- 对于MLPTI神经发育,特别是男孩的神经发育,需要进一步的长期跟踪和研究.
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