肥胖和BMI分数作为尿病的危险因素:超过30年的系统性审查
Megha Garg1, Philip Joseph2, Hans Johnson3
1Honorary Research Associate, Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym, Bristol.
Current opinion in urology
|May 6, 2025
概括
高体重指数 (BMI) 和肥胖与结石疾病 (KSD) 的风险增加有关. 建议通过改变生活方式和药物来管理KSD作为一种代谢状况,以减少复发.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 代谢疾病 代谢疾病
- 公共卫生 公共卫生
背景情况:
- 肥胖和高体重指数 (BMI) 是普遍存在的全球健康问题.
- 结石疾病 (KSD) 是一个重要的健康问题,发病率越来越高.
- 了解BMI和KSD之间的关系对于公共卫生战略至关重要.
研究的目的:
- 系统地审查和综合高BMI,超重,肥胖和结石疾病 (KSD) 发生率之间的联系的证据.
- 评估当前关于体重对KSD风险的影响的科学文献.
主要方法:
- 按照系统审查和元分析 (PRISMA) 准则的首选报告项目进行了系统审查.
- 在多个数据库 (科克兰图书馆,EMBASE,MEDLINE等) 中进行了全面的搜索. 对于相关的英语人口研究.
- 包括到2024年10月发表的研究,涉及报告高BMI,肥胖,超重和KSD发病率的成年人 (≥18岁).
主要成果:
- 在叙事综合中包括了15项研究,其中包括97,645名参与者和17,158例KSD病例.
- 在研究队列的基线特征中发现了显著的异质性.
- 13项研究比较了肥胖与非肥胖个体的石头发生情况,结果显示不同分析中KSD风险较低,较高或相似.
结论:
- 证据支持高BMI,超重,肥胖和患结石疾病的风险增加之间的积极关联.
- 应该将KSD视为一种代谢性疾病,需要综合治疗方法.
- 治疗策略应包括饮食调整,运动,药物治疗,以及高血压和糖尿病等并发性疾病的管理,以减轻KSD复发.
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