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Updated: May 15, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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衰老到热的纳米调器:导航瘤炎症微环境,用于增强免疫治疗

Jun Da1, Haolan Hu1, Linlin Wang1

  • 1Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan 410082, China.

Nano letters
|May 6, 2025
PubMed
概括

这项研究引入了一种纳米调器,将衰老的瘤细胞转化为免疫激活剂,有效地逆转与癌症相关的慢性炎症 (CCI) 和免疫抑制性瘤微环境 (TME). 这种方法增强了抗瘤效果,特别是与PD-1阻塞疗法相结合时.

关键词:
人工反应的人工反应.与癌症有关的慢性炎症.热致灭 (pyroptosis) 是一种致的过程.衰老代谢 代谢 衰老代谢瘤免疫力 免疫力

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