1型和2型糖尿病的新发病COVID-19后感染:系统性审查
Ahmed El-Naas1, Omar Hamad1, Siddhant Nair1
1Department of Medical Education, Weill Cornell Medicine-Qatar, Doha, Qatar.
Emerging microbes & infections
|May 6, 2025
概括
新发型糖尿病,包括1型 (T1DM) 和2型 (T2DM),是潜在的长期COVID并发症. 这项研究发现,COVID-19后新型糖尿病的患病率为1.37%,T2DM更为常见.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- COVID-19可能会导致除呼吸道症状之外的长期健康问题,称为长期COVID.
- 新发型糖尿病,表现出1型 (T1DM) 和2型 (T2DM) 的特征,已在COVID-19感染后的患者中观察到.
研究的目的:
- 为了识别和分析COVID-19感染后报告的新发糖尿病病例.
- 为了确定COVID-19后发展的糖尿病的患病率和特征.
主要方法:
- 在多个数据库中进行了全面的文献搜索.
- 报告T1DM或T2DMCOVID-19后感染的研究被选,数据被提取并由两个独立审查员交叉检查.
- 43项研究符合分析的纳入标准.
主要成果:
- 在COVID-19后,新发糖尿病的总体患病率为1.37%.
- 与1型糖尿病 (T1DM) (0.017%) 相比,2型糖尿病 (T2DM) 的患病率较高 (0.84%).
- 确定的风险因素包括SARS-CoV-2变种类型,患者年龄,并发症和疫苗接种状态.
结论:
- 感染COVID-19与患上新发糖尿病的风险增加有关.
- 潜在的机制包括直接对胰腺β细胞的病毒损伤,炎症和皮质类固醇的使用.
- 跨学科的方法对于管理后COVID患者至关重要,解决糖尿病等代谢并发症.
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