严重病患者的尿尿素,平衡和死亡率 - - 一项前性队列研究
Raquel Stocker Pérsico1, Marina Verçoza Viana2, Sérgio Henrique Loss2
1Programa de Pós-Graduação em Ciências Médicas: Endocrinologia. Faculdade de Medicina. Universidade Federal do Rio Grande do Sul.
Nutricion hospitalaria
|May 6, 2025
概括
平衡 (NB) 和尿路标志物与重症患者的死亡率无关. 需要进一步的研究来确定ICU中平衡的预后值.
科学领域:
- 关键护理医学 关键护理医学
- 营养生理学 营养生理学
- 生物标志物研究 生物标志物研究
背景情况:
- 平衡 (NB) 衡量了的摄入与排泄.
- 它在重症患者的预后效用仍未确定.
- 这项研究研究了NB和尿路参数作为ICU环境中不良结果的预测因素.
研究的目的:
- 评估平衡 (NB),尿道尿素 (UUE) 和尿道肌素 (UCE) 排泄之间的关系.
- 评估这些标志物与重症监护室 (ICU) 患者的不良结果之间的关系.
- 确定NB和尿路参数在ICU死亡率和其他临床结果中的预后值.
主要方法:
- 在ICU入院的第一周测量了平衡 (NB),尿尿素 (UUE) 和尿素 (UCE) 排泄量.
- 主要结局是ICU死亡率;次要结局包括机械通风持续时间,ICU/住院长度和住院死亡率.
- 用接收器操作特征 (ROC) 曲线来评估预测准确性.
主要成果:
- 包括127名患者;在第一次测量中,77.2%的NB呈阴性.
- 蛋白质摄入量在测量之间有显著差异 (40g/天而不是86g/天).
- 在NB,UUE或UCE和ICU/医院死亡率之间没有发现显著的关联;ROC曲线显示没有可靠的切断点.
结论:
- 平衡 (NB),尿尿素 (UUE) 和尿素 (UCE) 在这个队列中与ICU或医院死亡率无关.
- 作为重症患者的NB标记物的预后价值需要进一步调查.
- 需要进行额外的研究来澄清NB在重症监护中的临床效用.
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