冠状动脉疾病中的肥胖悖论:全国住院患者样本分析
Ali Salman1, Muhammad Saad, Ruqiat Masooma Batool
1Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Coronary artery disease
|May 6, 2025
概括
在冠状动脉疾病 (CAD) 患者中,较高的体重指数 (BMI) 与较低的住院死亡率有关,而体重不足的患者则面临更高的风险. 这表明增加BMI在CAD结果中具有保护作用.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 肥胖医学 肥胖医学
背景情况:
- 肥胖是冠状动脉疾病 (CAD) 的已知危险因素之一.
- 身体质量指数 (BMI) 对CAD患者医院治疗结果的具体影响需要进一步澄清.
研究的目的:
- 研究BMI类别与患有CAD的成年患者医院治疗结果之间的关联.
- 为了确定不同的BMI水平是否会影响CAD患者的死亡率,停留时间和医疗费用.
主要方法:
- 使用了来自国家住院患者样本数据库 (2018-2020) 的数据,用于成人CAD患者.
- 患者被分为六个BMI类别:体重不足,正常体重,超重和肥胖等级I,II和III.
- 采用多变量逻辑和线性回归分析来评估BMI对住院死亡率,住院时间 (LOS) 和总费用的影响.
主要成果:
- 分析了3,693,570次住院治疗;体重不足患者的死亡率最高 (6.8%),其次是正常体重 (5.2%).
- 与体重正常的人相比,超重和肥胖患者的住院死亡率调整后的几率较低 (ORs从0.54到0.78).
- 体重不足和体重正常的患者的住院时间中位数最长,而超重患者的总费用最高.
结论:
- 体重不足与CAD患者在医院住院死亡风险增加有关.
- 较高的BMI (超重和肥胖) 似乎具有保护作用,与CAD患者的住院死亡率较低相关.
- 在冠状动脉疾病患者中,BMI显著影响医院结果,包括死亡率和成本.
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