植物性饮食的质量与甲状腺功能障碍风险之间的关联
Juanjuan Zhang1, Yuchuan He1, Zhiyuan Tang2
1School of Public Health, Hebei University, Baoding, China.
Food & function
|May 6, 2025
概括
不健康的植物性饮食指数 (uPDI) 与增加甲状腺功能障碍 (TD) 和甲状腺功能低下风险有关. 相反,健康的植物性饮食指数 (hPDI) 与甲状腺功能障碍风险降低有关.
科学领域:
- 营养科学 营养科学
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 植物性饮食通常与降低慢性疾病风险有关.
- 关于植物性饮食质量和甲状腺功能障碍 (TD) 风险的前性证据有限.
- 这项研究调查了植物性饮食与TD风险之间的联系.
研究的目的:
- 检查植物性饮食指数与甲状腺功能障碍 (TD) 风险之间的纵向关联.
- 区分总体,健康和不健康的植物性饮食对TD,甲状腺功能低下和甲状腺功能过高的影响.
主要方法:
- 利用了199382名最初没有TD的参与者的英国生物库数据.
- 从17个食品组计算了三个植物性饮食指数 (PDI,hPDI,UPDI).
- 采用了Cox的比例危险模型来评估协会在平均12.0年的随访时间内.
主要成果:
- 较高的不健康植物性饮食指数 (uPDI) 与TD (HR 1.11) 和甲状腺功能低下症 (HR 1.14) 的风险增加相关.
- 较高的健康植物性饮食指数 (hPDI) 与甲状腺功能障碍的风险降低有关 (HR 0.84).
- 在分层和灵敏度分析中,研究结果保持一致.
结论:
- 不健康的植物性饮食模式 (高UPDI) 与甲状腺功能障碍和甲状腺功能低下的风险增加有关.
- 一种健康的植物性饮食模式 (高hPDI) 与甲状腺功能障碍的风险降低有关.
- 饮食质量对甲状腺健康起到作用,需要进一步研究.
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