预后营养指数在患有深部空间感染的患者中的价值
Fcs Kundi1,2, Z B Paksoy2
1Department of Otorhinolaryngology, Ankara Yildirim Beyazit University, Çankaya, Ankara, Turkey.
Nigerian journal of clinical practice
|May 6, 2025
概括
预后营养指数 (PNI) 可以预测抗生素耐药性和深部感染的住院时间. 较低的PNI表明耐药性风险更高,恢复时间更长,指导个性化治疗.
科学领域:
- 传染性疾病 传染性疾病
- 临床营养学 临床营养学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 抗生素治疗对于深部空间感染至关重要.
- 不适当的抗生素使用和耐药性会对患者的结果产生负面影响.
- 识别预后标志物对于有效管理至关重要.
研究的目的:
- 评估预后营养指数 (PNI) 作为预后标志物的临床意义.
- 评估PNI预测抗生素耐药性的能力.
- 为了确定PNI与住院时间的相关性.
主要方法:
- 分析了81名患有深部空间感染的住院患者的数据.
- 使用血清白蛋白和淋巴细胞计数计算PNI.
- 主要结局:抗生素耐药性;次要结局:停留时间.
主要成果:
- 抗生素耐药性患者的PNI显著降低 (47.3比57.5,P<0.001).
- PNI是抗生素耐药性的重要预测因素 (OR = 0.908,P = 0.004).
- 较低的PNI与长时间住院相关 (调整R平方=0.40,P=0.010).
结论:
- PNI是深部空间感染的有价值的预后标志物.
- 较低的PNI预测抗生素耐药性和更长的住院时间.
- PNI反映了营养和免疫状况,有助于个性化治疗策略.
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