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Updated: Jun 14, 2025

A High-throughput, High-content, Liquid-based C. elegans Pathosystem
09:44

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具有三重威胁的抗寄生虫药物:向寄生虫酶,质子动力和宿主细胞介导的杀死

Akanksha M Pandey1, Satish R Malwal1, Mariana Valladares-Delgado2,3

  • 1Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.

ACS infectious diseases
|May 6, 2025
PubMed
概括

结核病候选药物SQ109模拟物MeSQ109对具有低宿主细胞毒性的Leishmania寄生虫表现出强烈的活性. 这种药物向寄生虫线粒体和酸体,为治疗莱什曼病提供了一个有前途的新途径.

关键词:
查加斯病是查加斯病的一种疾病.在PMF中,PMF是指PMF.在 SQ1099 中使用.酸酸酸酸酸酸酸莱什曼尼亚病是一种病.疟疾 疟疾 是一种疾病.

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