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Updated: Jul 12, 2026

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一种银化物成分通过自性溶酶体通路改善了Aβ和Tau的聚合

Chengmu Zhao1,2, Juan Yue1, Yu Xie1,2

  • 1School of Pharmacy, Lanzhou University, No. 199 Donggang West Road, Lanzhou, Gansu, 730000, China.

Molecular neurobiology
|May 6, 2025
PubMed
概括

金色化物SUMI通过增强C. elegans的自-溶酶体通路来对抗阿尔茨海默病. 这个过程清除有毒的蛋白质聚合物,为阿尔茨海默病提供了潜在的治疗策略.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.自细胞体自细胞体自自是一种自的过程.金色化物成分的组成类似于饥饿的效应.

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Autophagy01:27

Autophagy

Autophagy is a self-digesting process by which a cell protects itself from threats both within and outside the cell, ranging from abnormal proteins to invading bacteria. In this process, obsolete components of the cell and invading microbes are degraded by hydrolytic enzymes active in an acidic environment of the lysosomal lumen.
An autophagic pathway consists of a series of signaling events activated in response to diverse stress and physiological conditions such as food deprivation,...