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转化疗法暴露和心血管疾病风险增加

James K Gibb1, Joshua M Schrock2,3, Madison Shea Smith2,4

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性取向和性别认同改变努力 (SOGICE) 对性和性别少数群体年轻成年人的心血管健康产生负面影响. 暴露于SOGICE与高血压和炎症有关,强调需要采取保护性政策.

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科学领域:

  • 公共卫生 公共卫生
  • 心血管健康 心血管健康
  • 在LGBTQ+健康方面

背景情况:

  • 性取向和性别认同改变努力 (SOGICE) 或转换疗法,尽管被毁和有害,但仍然存在.
  • 压力加剧了心血管疾病的风险,使SOGICE成为SGM健康的关键因素.

研究的目的:

  • 调查SOGICE暴露与性与性别少数群体 (SGM) 年轻成年人心血管疾病风险之间的关联.
  • 了解SOGICE对血压,全身炎症和高血压的影响.

主要方法:

  • 在芝加哥,对SGM年轻成年人进行的观察性队列研究 (RADAR),在出生时被分配为男性 (AMAB).
  • 对SOGICE暴露,血压 (DBP,SBP),全身炎症 (SI) 和自我报告的高血压 (HHBP) 的横截面数据收集.
  • 调整了社会人口统计学和行为共变量的回归分析.

主要成果:

  • 分析了703名SGM年轻成年人 (10.2%暴露于SOGICE).
  • 与未接触者相比,暴露于SOGICE的参与者表现出更高的SI,更高的DBP和SBP,以及更高的HHBP概率.
  • 在对共变量进行调整后,关联仍然显著.

结论:

  • SOGICE暴露与SGM年轻成年人的不良心血管健康指标有关.
  • 这些发现支持公共卫生和政策干预措施,以禁止SOGICE实践.
  • 解决SOGICE的心血管影响对于减少SGM健康差异和促进肯定性护理至关重要.