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Updated: May 9, 2025

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作为向STING-依赖性炎症的抑制剂的醇衍生物的开发

Peng Zhou1, Gen Yang1, Yan Wang1

  • 1Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, PR China.

Bioorganic & medicinal chemistry
|May 6, 2025
PubMed
概括

研究人员开发了针对干扰素基因刺激器 (STING) 途径的新型醇衍生物. 化合物4dc在小鼠中显示出强大的STING抑制和减少损伤,提供了一种新的抗炎治疗策略.

关键词:
抗炎剂是一种抗炎剂.H151 沙尔病毒 沙尔病毒印度尔衍生品 印度尔衍生品炎症 炎症是一种炎症.这是一种STING抑制剂.

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