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相关概念视频

Exon Recombination02:32

Exon Recombination

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The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon...
3.5K
Gene Conversion02:08

Gene Conversion

9.6K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
9.6K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

7.8K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
7.8K
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

5.9K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
5.9K
Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

26.7K
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
26.7K
Overview of Transposition and Recombination02:13

Overview of Transposition and Recombination

15.0K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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相关实验视频

Updated: May 9, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

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898

进化:基因重复使用...再次!

Nicholas W VanKuren1

  • 1Department of Ecology and Evolution, The University of Chicago, Chicago, IL 60637, USA.

Current biology : CB
|May 6, 2025
PubMed
概括
此摘要是机器生成的。

基因的进化再利用推动了动物特征的多样性. 一个单一的转录因子.

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Molecular Evolution of the Tre Recombinase
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Molecular Evolution of the Tre Recombinase

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In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity

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科学领域:

  • 进化生物学是进化的生物学.
  • 遗传学 遗传学 是一个
  • 分子生物学分子生物学

背景情况:

  • 遗传变异是动物特征多样性的关键驱动力.
  • 特定基因的进化再利用背后的机制仍然不完全理解.

研究的目的:

  • 研究使某些基因易于进化重复使用的因素.
  • 探索单个转录因子的进化如何促进适应变异.

主要方法:

  • 对不同动物血统的遗传变异的分析.
  • 研究一种特定的转录因子在特征进化中的作用.

主要成果:

  • 少数基因占有显著的动物特征多样性.
  • 单个转录因子的演变是适应变异的基础.
  • 这在微观和宏观进化尺度上的变化背后.

结论:

  • 特定的基因易于进化重复使用.
  • 转录因子进化是产生适应性特征的重要机制.
  • 这种机制在不同的进化时间尺度上运行.