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Updated: May 9, 2025

Preparation of Mica Supported Lipid Bilayers for High Resolution Optical Microscopy Imaging
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m6A改变了核糖体的动态,从而启动了mRNA的降解

Shino Murakami1, Anthony O Olarerin-George2, Jianheng Fox Liu1

  • 1Department of Pharmacology, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA.

Cell
|May 6, 2025
PubMed
概括

在mRNA中的N6-甲基氨酸 (m6A) 触发了核糖体的停滞和碰撞,从而启动了mRNA的降解. 这一过程对于细胞生长和应激反应至关重要, 核糖体作为最初的m6A传感器.

关键词:
甲基氨酸时间间隔-seq适应性反应氨基酸耗尽m(6) 一个mRNA 衰变mRNA 降解mRNA 稳定性核糖体碰撞核糖体停滞时间

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