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Updated: May 12, 2025

Preparation of Mica Supported Lipid Bilayers for High Resolution Optical Microscopy Imaging
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在A/IGF2BP3驱动的血清生物合成中,有助于AML的根性和代谢脆弱性

Feng Huang1,2,3, Yushuai Wang2, Xiuxin Zhang3,4

  • 1The First Affiliated Hospital, The Fifth Affiliated Hospital, State Key Laboratory of Respiratory Diseases, Guangzhou Medical University, Guangzhou, China.

Nature communications
|May 6, 2025
PubMed
概括

RNA N6 - 甲基氨酸 (m6A) 修饰调节了急性髓性白血病 (AML) 中的血清蛋白合成. 削减IGF2BP3,一个m6调节器,使AML细胞对氨酸和甘氨酸缺乏敏感,提供了一个潜在的治疗策略.

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The identity of a substance is defined not only by the types of atoms or ions it contains but by the quantity of each type of atom or ion. For example, water, H2O, and hydrogen peroxide, H2O2, are alike in that their respective molecules are composed of hydrogen and oxygen atoms. However, because a hydrogen peroxide molecule contains two oxygen atoms, as opposed to the water molecule, which has only one, the two substances exhibit very different properties.
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Thomson's e/m Experiment01:19

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In a beam of charged particles created by a heated cathode, the particles move at different speeds. However, many applications need a beam with uniform particle speeds. An arrangement known as a velocity selector uses electric and magnetic fields to pick particles with a particular speed from the beam.
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Magnetic flux depends on three factors: the strength of the magnetic field, the area through which the field lines pass, and the field's orientation with respect to the surface area. If any of these quantities vary, a corresponding variation in magnetic flux occurs. If the area through which the magnetic field lines are passing changes, then the magnetic flux also changes. This change in the area can be of two types: the flux through the rectangular loop increases as it moves into the...
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Knowing how to determine the moment of inertia in a wheel's axle can be invaluable in engineering and automotive applications. It provides an understanding of how changes in geometry, mass, and radius can impact its performance.
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Masonry in Cold and Hot Weather Conditions01:21

Masonry in Cold and Hot Weather Conditions

In cold weather, masonry construction requires specific precautions to ensure mortar does not freeze before curing, as this can significantly weaken its strength and watertightness. Mortar temperature should be maintained between 60°F and 80°F to support proper hydration and curing. Below 40°F, mortar water must be heated, but should not exceed 120°F as high temperatures can reduce mortar's compressive and bond strength.
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In hot, dry climates, the thermal mass of masonry walls can be beneficial, absorbing heat during the day and releasing it at night, thereby stabilizing indoor temperatures. However, in most other climates, additional insulation is necessary to enhance thermal resistance.
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