由弹装载的核心针活检装置诱导的化活动
Jussi Kiviluoto1, Maxime Fauconnier2, Heikki J Nieminen3
1Medical Ultrasonics Laboratory (MEDUSA), Department of Neuroscience and Biomedical Engineering, Aalto University, 02150, Espoo, Finland. jussi.i.kiviluoto@aalto.fi.
Scientific reports
|May 6, 2025
概括
核心针活检器件可以在组织采样过程中引起腔化或泡形成. 这项研究监测了水和组织幽灵中的洞穴,发现它因针设计和材料密度而异,为新的成像应用提供了潜力.
科学领域:
- 生物医学工程 生物医学工程
- 声学 声学 在声学方面
- 医疗器械技术 医疗器械技术
背景情况:
- 核心针活检对于病理学评估至关重要,通常使用弹装载装置.
- 这些设备的动力学可以诱导化,这种现象具有已知的机械效应.
- 活检过程中的洞穴在很大程度上没有得到充分的研究.
研究的目的:
- 描述和量化与核心针活检器件相关的化现象.
- 为了研究针设计和组织特性对化的影响.
- 探索活检诱导的洞腔的潜在应用和安全影响.
主要方法:
- 采用了视觉和声学监控技术.
- 实验使用脱离离子水和基于阿加罗斯的组织模仿幻体进行.
- 测试了针的振荡 (纵向/曲向) 和不同度的亚加罗斯.
主要成果:
- 洞穴在水中的侧切针最为突出,但在前切针中也存在.
- 化强度随着糖度的增加而降低,在1.0%w/v时被消除.
- 在两种针类型的可听和超声波频率中检测到声学辐射.
结论:
- 在液体和模仿组织的材料中,弹载核针活检器件的运行过程中会发生化.
- 化为新的体内超声波成像应用提供了机会.
- 了解洞腔对于对活检器件的安全性评估至关重要.
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