患有先前前肠外科手术的患者食管切除术的结果:一个匹配的回顾性队列研究
Agustina A Pontecorvo1, Jorge Cornejo1, Mohammad Alomari1
1Division of Advanced Gastrointestinal and Bariatric Surgery, Department of General Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Surgical endoscopy
|May 6, 2025
概括
以前的前肠外科手术 (PFS) 并没有增加食道切除术后的并发症. 因癌症而接受食道切除术的PFS患者表现出更好的生存趋势,可能是由于早期诊断.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 胸部外科手术 胸部外科手术
背景情况:
- 食道切除术是一种复杂的手术程序,用于食道癌和良性疾病.
- 先前前肠外科手术对食道切除术结果的影响需要进一步调查.
研究的目的:
- 评估先前前肠外科手术 (PFS) 对经过食道切除术的患者手术后结果的影响.
- 为了比较PFS和无PFS患者之间的并发症率,手术时间和存活率.
主要方法:
- 对食道切除术患者 (2008-2024) 的回顾性队列研究.
- 患有PFS的患者 (N=37) 与没有PFS的患者 (N=111) 用近邻方法匹配1:3.
- 卡普兰-梅尔分析评估了生存率和免于长期并发症.
主要成果:
- 与没有PFS组 (426分钟;p=0.038) 相比,PFS组的操作时间 (463分钟) 显着更长.
- 在转换为开放性手术,早期并发症,重新干预或泄漏率方面没有发现显著差异.
- 在PFS组中观察到较低的解剖管狭窄的趋势,PFS癌症患者的生存率更高 (p=0.06).
结论:
- 以前的前肠外科手术不会对食道切除的结果产生不利影响,也不会增加并发症风险.
- 在之前进行过前肠外科手术的患者中,食管切除术是安全的.
- 患有PFS和食道癌症的患者可能有更好的存活率,这是由于在频繁的随访中更早发现疾病.
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