护士在门诊内镜检查期间对护士服用的普罗波福尔的不良反应的危险因素:一个横截面研究
Renzo Inca Villanueva1, Cynthia Bazán Montero2, María Estela Bulnes-Montánchez2
1Escuela Profesional de Medicina Humana, Universidad Privada San Juan Bautista, Lima, Peru.
BMC anesthesiology
|May 6, 2025
概括
在门诊内镜检查中,护士施用的普罗波镇静剂通常是安全的,其中30.9%的人经历了轻度至中度的不良药物反应 (ADR). 较长的程序和ASA III状态增加了ADR风险,需要仔细监测.
科学领域:
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
- 患者安全 患者安全
背景情况:
- 内镜手术对于胃肠道的诊断和管理至关重要.
- 普罗波是一种常见的门诊镇静剂,以快速开始和恢复而闻名.
- 尽管它具有安全性,但可导致药物不良反应 (ADRs).
研究的目的:
- 为了调查由护士管理的普罗波福尔镇静剂引起的ADRs的流行率.
- 在秘鲁的门诊内镜手术中识别ADRs的风险因素.
- 评估这些不良反应的严重程度和特征.
主要方法:
- 追溯对919名秘鲁患者的回顾,这些患者在普罗波镇静下接受了内镜手术.
- 纳入标准:年龄18-69岁,ASA身体状态I-III,血液动力学稳定.
- 收集关于副作用,严重程度,因果关系的数据,并在p < 0.05时进行统计分析.
主要成果:
- 在693名被纳入试验的患者中,有30.9%的患者经历了至少一个ADR,主要是心血管或呼吸系统事件 (低血压,缺氧).
- 副作用大多为轻度 (64.2%) 或中度 (35.8%);没有报告严重事件.
- 副作用的重要风险因素包括ASA III状态 (PRa=1.73) 和手术时间>20分钟 (PRa=2.05).
结论:
- 护士为门诊内镜进行的普罗波镇静剂通常是安全的,但存在风险.
- 在长时间的手术和ASA III患者中,定期监测生命指标至关重要.
- 这些发现强调了警监测的重要性,以减轻这种环境中的不良反应.
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