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生命的简单7,生命的基本8和生命的关键9的比较歧视:评估增加复杂性对死亡率预测的影响
Xu Zhu1, Iokfai Cheang1, Yiyang Fu1
1State Key Laboratory for Innovation and Transformation of Luobing Theory, Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, 210029, China.
BMC medicine
|May 6, 2025
概括
生命的简单7 (LS7),生命的基本8 (LE8) 和生命的关键9 (LC9) 有效地预测死亡率. 由于其可比性能和更简单的结构,LS7是一个实用的工具.
科学领域:
- 心血管健康和死亡率预测
- 公共卫生和预防医学
背景情况:
- 心血管健康 (CVH) 对死亡结果至关重要,但各种CVH指标的比较有效性尚不清楚.
- 现有的指标包括Life's Simple 7 (LS7),Life's Essential 8 (LE8),增加睡眠,以及Life's Crucial 9 (LC9),增加心理健康.
研究的目的:
- 评估LE8和LC9是否与LS7.7相比提供了更好的死亡率预测.
- 在CVH指标中评估睡眠和心理健康领域的增量价值.
主要方法:
- 使用考克斯回归分析对22,382名NHANES参与者 (2005-2018) 的分析.
- 评估LS7,LE8,LC9得分与所有原因,心脑血管疾病 (CCD) 和心血管疾病 (CVD) 死亡率之间的关联.
- 使用接收器运行特征 (ROC) 曲线和曲线下的面积 (AUC) 评估预测性能.
主要成果:
- 较高的LS7,LE8和LC9得分与明显较低的全因,CCD和CVD死亡率有关.
- 与LE8和LC9 (0.68对0.67) 相比,LS7在5年全因死亡率预测中的AUC略高.
- 所有指标都在5年内略有改善了基线所有原因死亡率预测,整体表现几乎相同.
结论:
- LS7,LE8和LC9都是死亡率的有效预测指标.
- 由于其可比的预测准确性和更简单,更实用的评分系统,建议LS7用于临床和公共卫生应用.
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