使用微生物培养和抗生素检查结果对选择性干牛治疗新方法的评估
Hossein Navaei1, Mehdi Vodjgani2, Babak Khoramian3
1Department of Theriogenology, Faculty of Veterinary Medicine, University of Tehran, Qareeb Str., Azadi Ave, Tehran, Iran.
BMC veterinary research
|May 6, 2025
概括
使用单个培养和抗生素检查结果的选择性干牛疗法 (DCT) 显著改善了乳牛的治愈率,并减少了乳牛的新的乳内感染和临床乳腺炎. 这种有针对性的方法为管理牛乳腺炎提供了好处.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 动物科学动物科学
- 微生物学 微生物学
背景情况:
- 抗菌素耐药性增加需要更新干牛治疗 (DCT) 策略.
- 财务考虑和有效性推动了对新型DCT方法的研究.
- 基于个体牛诊断的选择性治疗正在探索中.
研究的目的:
- 用培养和抗生素检查结果来评估选择性DCT方法.
- 评估选择性DCT对乳腺炎指数,治愈率和感染发生率的影响.
- 为了确定在牛奶中前30天 (DIM) 对牛奶产量的影响.
主要方法:
- 选择了291只具有高体细胞计数和阳性牛奶培养的荷尔斯坦牛.
- 牛奶样本在干燥前和分娩后进行培养;测量体细胞计数 (SCC).
- 牛被随机分为对照组 (标准DCT) 和治疗组 (选择性DCT).
主要成果:
- 选择性治疗组显示出明显更高的治愈率 (P=0.0006).
- 在治疗组中,新的乳内感染 (IMI) 和临床乳腺炎的发病率显著下降 (分别P=0.0006和P=0.015).
- 在哺乳期开始时,群体之间没有观察到SCC或牛奶产量的显著差异.
结论:
- 基于个人牛奶培养和抗生素检查结果的选择性DCT是有益的.
- 这种有针对性的策略增加了病原体治愈率.
- 它有效地降低了新的IMI和临床乳腺炎的发病率在前30 DIM内.
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