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Updated: May 12, 2025

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阿伦德罗纳酸重新定位为潜在的抗寄生剂,准Trichinella spiralis无机酸盐酶,在体外支持分子对接和分子动力学模拟研究

Marmar A Hanafy1, Doaa A Nassar1, Fatima M Zahran1

  • 1Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

BMC chemistry
|May 6, 2025
PubMed
概括

阿伦德罗纳酸 (ALN) 是一种双酸盐,通过破坏它们的表面蛋白质,有效地杀死Trichinella spiralis寄生虫. 这种药物的重新用途显示出对治疗三菌病的希望,这是一个重大的全球健康问题.

关键词:
三螺旋螺旋菌 (Trichinella spiralis) 是一种螺旋螺旋菌.阿尔本达 (Albendazole) 是一种可以艾伦德罗纳酸盐是一种酸盐.分子对接是分子对接.模拟分子动力学模拟扫描电子显微镜扫描电子显微镜

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