慢性 chikungunya 关节痛患者的功能缺陷相关的临床变量:一个横截面研究
Joanna Sacha Cunha Brito Holanda1, Eduarda Fonseca Mendes2, Edson Silva-Filho2
1Graduate Program in Physical Therapy, Federal University of Rio Grande do Norte, Rio Grande do Norte, Brazil.
概括
奇孔古尼亚病毒感染会导致慢性疼痛和残疾. 这项研究发现,老年和更高的疼痛强度预测了 chikungunya 关节痛患者的结果更差.
科学领域:
- 病毒学 病毒学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- Chikungunya 病毒 (CHIKV) 是一种全球性的树冠病毒,导致衰弱的炎症性关节痛,功能失能和疼痛.
- 慢性 chikungunya 关节痛显著影响患者的生活质量和日常功能在世界各地.
研究的目的:
- 确定预测慢性 chikungunya 关节痛患者功能能力变化的关键因素.
- 了解 chikungunya 患者疼痛,睡眠和身体健康之间的关系.
主要方法:
- 一项涉及119名感染 chikungunya 病毒的个体的横截面研究.
- 使用了经过验证的工具,包括健康评估问卷 (HAQ),视觉模拟量表 (VAS),简要疼痛清单 (BPI),匹兹堡睡眠质量指数 (PSQI) 和SF-36健康调查.
- 使用回归分析来确定功能能力的重要预测因素.
主要成果:
- 高龄和更高的简要疼痛库存 (BPI) 强度得分是较高视觉模拟量表 (VAS) 疼痛得分的显著预测因素 (R平方:0.257).
- 对于健康评估问卷 (HAQ) 评分,年龄较大,匹兹堡睡眠质量指数 (PSQI) 评分较差,SF-36身体健康评分较低是显著的预测因素 (R平方:0.316).
结论:
- Chikungunya 病毒感染呈现复杂的症状,疼痛和残疾之间存在显著的关联.
- 年龄,疼痛强度,睡眠质量和身体健康状况是影响慢性 chikungunya 关节痛的功能能力的关键因素.
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