生物反训练与用于治疗异能排便的博托克斯注射相比:一个随机对照试验
Noha Emad1, Hosam Ghazy Elbanna1, Ahmed AbdelMawla1
1Department of General Surgery, Faculty of Medicine-Mansoura University, Mansoura, Egypt.
概括
生物反 (BFB) 和甲型玻尿素毒素 (BTX-A) 两者都能控制不协同的排便. BFB显示出更好的短期症状缓解,而BTX-A改善了直肠功能.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 胃肠病学 胃肠病学
- 盆地地板功能障碍 盆地底功能障碍
背景情况:
- 失同性排便 (DD) 涉及由于 puborectalis 肌肉和外部关节功能障碍而导致直肠疏散受损.
- 这种情况会导致慢性便秘和便障碍,显著降低患者的生活质量.
- 目前的管理策略需要进行比较分析,以获得最佳的患者结果.
研究的目的:
- 为了比较生物反 (BFB) 训练与毒素A型 (BTX-A) 注射在管理异能排便中的有效性.
- 评估这些干预措施对便秘症状和直肠生理学的影响.
主要方法:
- 一项随机对照试验,涉及78名被诊断患有DD的患者.
- 第一组 (39名患者) 在1.5个月内接受了6次BFB治疗.
- 第二组 (39名患者) 接受了超声波引导的BTX-A注射.
主要成果:
- 两组之间干预前的韦克斯纳便秘分数 (WCS) 没有显著差异.
- BFB组在干预后的2周,1个月和3个月显示出WCS在统计学上显著的改善.
- 注射BTX-A显著减少了门裂的存在,并改善了直肠测量结果.
结论:
- 无论是BFB还是BTX-A都有效地管理了DD.
- BFB提供卓越的短期症状改善 (WCS).
- BTX-A在改善直肠生理参数方面显示出显著的好处.
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