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Updated: May 12, 2025

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
13:34

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缺陷NADK四基因突变体通过控制NADK活动影响肺癌对化疗的反应

Mengxue Hu1, Fuxing Wang2, Yue Zhu3,4

  • 1Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China.

Genes & diseases
|May 7, 2025
PubMed
概括

人类尼古丁胺胺腺因二核酸 (NAD+) 激酶 (NADK) 结构显示其四重体形式对活性至关重要. 突变影响NADK功能,影响癌症化疗耐药性和敏感性.

关键词:
化学疗法耐药性 抗化学疗法耐药性肺癌是一种肺癌.甲基化 甲基化 甲基化突变的NADK突变物.在NADK四聚合物中,NADK是四聚合物.

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