在中国六个城市的乳腺癌组合内分泌疗法趋势 (在2016-2021年)
Chen Wang1, Bo Chen1, Qin Chen1
1Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, People's Republic of China.
Risk management and healthcare policy
|May 7, 2025
概括
在中国,从2016年到2021年,针对乳腺癌的内分泌治疗的处方显著增加. 芳酶抑制剂 (AI) 和AI结合卵巢功能抑制 (OFS) 现在是最常见的治疗方法.
科学领域:
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 内分泌疗法是乳腺癌治疗的基石.
- 了解处方模式对于优化患者护理和资源配置至关重要.
研究的目的:
- 分析中国乳腺癌内分泌治疗处方趋势.
- 检查药物组合的不断变化的使用情况,特别是在绝经前和绝经后的妇女身上.
主要方法:
- 来自中国 (2016-2021) 的门诊处方数据的回顾性分析.
- 评估处方量,成本,定义的每日剂量 (DDD) 和定义的每日成本 (DDC).
- 对两种药物组合模式的分析,按更年期状态分层.
主要成果:
- 在2016年至2021年期间,处方量增加了49.6%,成本增加了85.2%.
- 埃克塞梅斯坦成为DDDs最常用的药物,而他莫西芬的使用量下降.
- 芳酶抑制剂 (AI) 和卵巢功能抑制 (OFS) 的组合显示使用量显著增加 (P=0.015).
结论:
- 对于乳腺癌的内分泌治疗使用在中国正在增加.
- 芳酶抑制剂 (AI) 是最常见的药物,AI加上卵巢功能抑制 (OFS) 是主要的组合疗法.
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