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Updated: May 12, 2025

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系统性和局部性硬化皮肤病患者的皮肤和上皮的组织病理学和分子分析

Betul Sozeri1, Seyma Turkmen1, Basak Yildiz Atikan2

  • 1Department of Pediatric Rheumatology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.

Northern clinics of Istanbul
|May 7, 2025
PubMed
概括

儿科硬化症的发病包括血和皮肤中转化生长因子β1 (TGF-β1) 的升高. 系统性病例显示出更明显的TGF-β1,而局部病例显示出纤维细胞反应限制.

关键词:
童年 童年 童年 童年硬化皮质硬化皮质 (scleroderma) 是一种疾病.转化增长因子β1的转化增长因子β1

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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