罗皮瓦卡因局部透用于甲状腺切除术后的疼痛控制:系统性审查和元分析
Ebraheem Albazee1, Fahad Allafi2, Abdulwahab Alsalem3
1Otorhinolaryngology-Head and Neck Surgery Kuwait Institute for Medical Specializations (KIMS) Kuwait City Kuwait.
罗皮瓦卡因局部透有效地减少了甲状腺切除术后的早期术后疼痛和阿片类药物消耗. 然而,它对缓解疼痛的益处在2小时后减少,并没有影响其他康复结果.
科学领域:
- 麻醉学 麻醉学
- 手术瘤学手术瘤学
- 药理学 药理学是指药理学的学科.
背景情况:
- 甲状腺切除术是一种常见的外科手术,与中度至重度的术后疼痛有关.
- 有效的疼痛管理对于患者在甲状腺切除术后的康复和满意度至关重要.
- 局部麻醉透是一种潜在的策略来管理手术疼痛.
研究的目的:
- 在接受甲状腺切除术的患者中评估罗皮瓦卡因局部透的止痛效果.
- 综合来自随机对照试验 (RCT) 关于罗皮瓦卡因在甲状腺切除术疼痛管理中的作用的证据.
主要方法:
- 进行了RCT的系统审查和元分析.
- 数据来源包括PubMed,谷歌学者,中央,斯科普斯和科学网.
- 分析的终点:疼痛严重程度,阿片类药物消耗,患者满意度,住院和PACU停留,手术持续时间和PONV发病率.
主要成果:
- 罗皮瓦卡因在甲状腺切除术后1-2小时显著减少疼痛 (SMD:-1.40).
- 在术后4至24小时内没有观察到疼痛的显著差异.
- 罗皮瓦卡因降低了阿片类药物消耗 (SMD: -0.75),但没有影响手术持续时间,住院/PACU,患者满意度或PONV发病率.
结论:
- 罗皮瓦卡因局部透提供短期止痛,并减少甲状腺切除术患者的阿片类药物使用.
- 有证据表明,长期缓解疼痛是有限的,对其他恢复参数没有重大影响.
- 可能需要进一步的研究来澄清罗皮瓦卡因在甲状腺切除术中的作用和最佳使用.
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