系统性免疫炎症指数与慢性自发性疹症严重程度的关系
Fikriye Kalkan1, Sait Yesillik1, Fevzi Demirel1
1Department of Immunology and Allergy, University of Health Sciences, Gulhane Training and Research Hospital, Ankara, 06018, Turkey.
概括
系统性免疫炎症指数 (SII) 与慢性自发性疹 (CSU) 患者的疹活动评分-7 (UAS-7) 相对应. 这种易于计算的标记可以预测疾病的严重程度和指导治疗.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 血液学 血液学 血液学
背景情况:
- 慢性自发性疹 (CSU) 呈现为持续超过六周的疹.
- 疾病的严重程度是使用疹活动评分-7 (UAS-7) 评估的.
- 系统性免疫炎症指数 (SII) 反映了通过常规血液计数的炎症和免疫状态.
研究的目的:
- 在CSU患者中调查系统免疫炎症指数 (SII) 和疹活动评分-7 (UAS-7) 之间的相关性.
主要方法:
- 一项研究包括245名被诊断患有CSU的患者.
- 所有参与者都记录了疹活动得分-7 (UAS-7).
- 根据UAS-7得分将患者分为四组,以评估与SII的相关性.
主要成果:
- 在UAS-7组之间观察到白细胞计数,中性粒细胞,血小板,中性粒细胞-淋巴细胞比率 (NLR),血小板-淋巴细胞比率 (PLR) 和SII的显著差异.
- 在SII,NLR,PLR和UAS-7分数之间发现了正相关性.
- 在SII和UAS-7之间发现了最强的相关性 (P<0.001,r=0.642).
结论:
- 系统性免疫炎症指数 (SII) 是一个实用,客观,易于计算的标记.
- SII可以有效地预测CSU的严重程度.
- SII有助于指导患者的随访和治疗策略.
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