脉冲率的复杂性降低与老年人的认知衰退速度更快有关
Chenlu Gao1,2,3, Andrew S P Lim4, Shahab Haghayegh1,2,3
1Department of Anesthesia, Critical Care and Pain Medicine Massachusetts General Hospital Boston Massachusetts USA.
Journal of the American Heart Association
|May 7, 2025
概括
脉率复杂性是对亚临床心血管功能的衡量标准,与老年人认知能力下降的缓慢有关. 更高的复杂性表明,随着时间的推移,更好的认知保存.
科学领域:
- 老年学是一门学科.
- 心脏病学 心脏病学
- 神经科学是一个神经科学.
背景情况:
- 心血管疾病与认知健康密切相关.
- 亚临床心血管变化,如心脏自主功能障碍,可以预测心血管疾病并帮助风险分层.
- 脉率监测是评估心脏周期和自主调节的常用方法.
研究的目的:
- 调查脉率复杂性与老年人纵向认知衰退之间的关联.
- 确定脉率复杂性是否作为与认知衰老相关的亚临床心血管功能的代理.
主要方法:
- 从503名老年人 (平均年龄82岁) 收集了过夜脉氧计数据.
- 使用分布式算法来量化脉冲率复杂度.
- 参与者在基线和随访时接受了认知测试;线性混合效应模型分析了关联.
主要成果:
- 脉冲率复杂度增加 (分布) 与全球认知衰退缓慢显著相关.
- 分布的1-SD增加与认知衰老大约3年缓慢相对应.
- 传统的脉率变化指标显示,与认知变化没有关联.
结论:
- 较高的脉率复杂性与在衰老中保持认知功能的相关性.
- 这一发现表明脉率复杂性可能是认知衰老的有价值指标.
- 需要进一步的研究来探索与神经退行性疾病和因果关系的联系.
相关概念视频
Cognitive Development During Adulthood
40
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
40
Decreased pulse rate
526
Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
526
Factors Influencing Heart Rate
2.2K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.2K
Pulse
409
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
409
Regulation of Pulse
1.2K
Pulse regulation involves physiological mechanisms that ensure adequate blood flow throughout the body. The heartbeat, regulated by the autonomic nervous system, is influenced by hormonal balance, physical activity, and emotional state.
1.2K
Special considerations while measuring pulse
551
Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
551


