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Updated: May 12, 2025

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卢克索利提尼布相互作用对JAK2 JH1域动态的影响

Hong Nhung Vu1, Ragousandirane Radjasandirane1, Julien Diharce1

  • 1Université Paris Cité and Université de la Réunion, INSERM, EFS, BIGR U1134, DSIMB Bioinformatics Team, F-75015 Paris, France.

International journal of molecular sciences
|May 7, 2025
PubMed
概括

像Ruxolitinib这样的Janus酶2 (JAK2) 抑制剂对于治疗骨髓增殖性瘤至关重要. 分子动力学模拟显示,鲁克索利提尼布稳定了JAK2 JH1域,抑制了它的活性.

关键词:
简氏酶抑制剂 简氏酶抑制剂基本的血栓细胞血症.分子动力学分子动力学骨髓扩散性瘤是什么酸化的方法是:光化.维拉多细胞血症 维拉多细胞血症蛋白质块可以阻断蛋白质.蛋白质连接物相互作用蛋白质结构 蛋白质结构脊髓大病是一种病.结构字母表结构字母表

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