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Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
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在清晰细胞癌中调节红素活性

Bojana B Beleslin Čokić1, Sandra Bižić Radulović2, Tijana Subotički3

  • 1Department for Sero and Molecular Diagnostics, Institute of Virology, Vaccines and Sera "Torlak", Vojvode Stepe 458, 11221 Belgrade, Serbia.

International journal of molecular sciences
|May 7, 2025
PubMed
概括

清细胞细胞癌 (ccRCC) 涉及VHL基因突变. 这项研究发现,低氧,而不是VHL,主要驱动ccRCC中的红色素 (EPO) 和EPOR激活.

关键词:
通过JAK2/STAT5A路径进行检测.清晰的细胞癌.红色素素是一种人体蛋白质.低氧诱导因子-1 诱导因子-1·希佩尔·林道夫 (Hippel·Lindau) 的一个基因.

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