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NAT2乙化状态预测抗结核治疗期间的肝毒性:多民族队列的累积风险分析

Marco Schiuma1, Sofia Dinegro2, Vera Battini2

  • 1Department of Infectious Disease, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.

International journal of molecular sciences
|May 7, 2025
PubMed
概括

抗结核药物诱导的肝毒性 (ATDH) 风险在缓慢的乙化剂中较高,这是由于N-乙转移酶2 (NAT2) 活性降低. 早期识别NAT2表型可以提高结核病治疗的安全性和有效性.

关键词:
这种酶是NAT2酶.乙化表型是一种乙化表型.抗结核药物 抗结核药物 抗结核药物遗传多形态主义是一种遗传多形态主义.肝毒性 肝毒性 肝毒性结核病是一种肺结核病.

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