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Updated: May 8, 2025

Analysis of Fecal Microbiota Dynamics in Lupus-Prone Mice Using a Simple, Cost-Effective DNA Isolation Method
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Analysis of Fecal Microbiota Dynamics in Lupus-Prone Mice Using a Simple, Cost-Effective DNA Isolation Method

Published on: May 2, 2022

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与全身性红斑狼风险相关的肠道微生物群和炎症性细胞因子的遗传责任:一个多omics研究

Rui-Ling Lu1, Yan-Ran Chen1, Xu-Fa Yang2

  • 1Department of Rheumatology and Immunology, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen, Guangdong, China.

Clinical rheumatology
|May 7, 2025
PubMed
概括

这项研究揭示了肠道细菌和系统性红斑狼 (SLE) 之间的因果关系. 特定的细胞因子,纤维细胞生长因子19 (FGF19) 和瘤坏死因子受体超级家族成员9 (TNFRSF9),调解这种关系,提供新的治疗途径.

关键词:
16S rDNA基因测序的基因测序细胞因子 (cytokines) 是一种细胞因子.我们的肠道微生物群.门德尔的随机化系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.

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