描述和抗氧化和红色保护作用的β-胡卜素复合体在β-环氧化中
Andrés Leobardo Puebla-Duarte1, Ariadna Thalía Bernal-Mercado1, Irela Santos-Sauceda2
1Departamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Blvd. Luis Encinas y Rosales S/N, Col. Centro, Hermosillo 83000, Sonora, Mexico.
International journal of molecular sciences
|May 7, 2025
概括
通过共同沉在β-cyclodextrin (β-CD) 中封装的β-胡卜素 (β-C) 增强了稳定性和生物活性. 由此产生的β-C/β-CD复合体具有显著的抗氧化和红色保护作用,适用于食品和制药应用.
科学领域:
- 材料科学 材料科学 材料科学
- 生物化学 生物化学
- 物理化学 物理化学
背景情况:
- β-胡卜素 (β-C) 是一种重要的营养素,由于其疏水性,溶解性低,以及因光和氧而降解,应用有限.
- β-cyclodextrin (β-CD) 是一种能够形成包容复合物的循环寡糖,为增强像β-C.C.这样的疏水化合物的稳定性和生物可用性提供了一个有前途的策略.
研究的目的:
- 为了表征使用共沉制备的β-胡卜素/β-环氧化 (β-C/β-CD) 纳入复合体.
- 评估开发的β-C/β-CD纳入复合物的抗氧化和红色保护活性.
主要方法:
- 采用共同沉技术,以40:60的比例合成β-C/β-CD含有复合物.
- 描述涉及紫外可见光谱,FT-IR,拉曼光谱,DSC,TGA,SEM,X射线衍射和泽塔电位测量.
- 使用ABTS,DPPH和FRAP测定来评估抗氧化活性,而通过测量血液溶解抑制来确定红色保护作用.
主要成果:
- 该β-C/β-CD复合体表现出高产率 (94.10%),捕获效率 (82.47%) 和负载效率 (11.92%) 的低水分含量 (2.93%).
- 光谱和热分析证实了成功的复合物形成,在216小时内观察到β-C释放.
- 这些复合物表现出与纯β-C相当的强有力的抗氧化活性和显著的红色保护作用 (64.09%的血液溶解抑制).
结论:
- β-环氧素有效地封装β-胡卜素,提高其稳定性并保持其生物活性.
- 具有特征的β-C/β-CD纳入复合体具有显著的抗氧化和红色保护性质.
- 这些发现表明β-C/β-CD纳入复合物的潜在应用在食品和制药行业.
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