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Updated: May 5, 2026

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探索脂质纳米粒子发展的挑战:体外-体外相关性差距

Sarah Lindsay1, Muattaz Hussain1, Burcu Binici1

  • 1Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.

Vaccines
|May 7, 2025
PubMed
概括

脂质纳米颗粒 (LNPs) 在体外和体内显示可变的mRNA表达,影响临床翻译. 综合评估对于优化治疗药物和疫苗的LNP输送系统至关重要.

关键词:
一个LNP就是LNP.表达方式表达方式表达方式在体外 (in vitro) 的情况下.在活体中,活体中脂质纳米颗粒的使用方法它们是mRNARNA.疫苗,疫苗的使用情况.

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