用分布和基方法确定威斯康星州石头生活质量调查问卷的临床重要差异最小值
Carl A Ceraolo1, David Song1, Victor Sandoval1
1Department of Urology, University of Rochester Medical Center, Rochester, New York, USA.
Journal of endourology
|May 7, 2025
概括
威斯康星州石头生活质量 (WISQOL) 调查问卷
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 健康 结果 研究 研究 结果
- 患者报告的结果
背景情况:
- 威斯康星州石头生活质量 (WISQOL) 调查问卷评估石病患者的与健康有关的生活质量.
- 估计WISQOL分数的临床重要差异最小值 (MCID) 对于解释患者结果至关重要.
- 之前的研究还没有为WISQOL工具确定一个最终的MCID值.
研究的目的:
- 使用基于分布和基于的方法来确定WISQOL问卷的MCID值.
- 为评估结石患者生活质量的有意义变化提供一个基准.
主要方法:
- 一个结石诊所的1197名患者的回顾性分析 (2018年1月 - 2023年11月).
- 收集了最初和后续访问的WISQOL分数,以及基线特征.
- 采用基于分布的方法和基于的方法 (横截面,纵向,集团内部和集团间),使用全球过渡问题.
主要成果:
- 基于分布的MCID估计范围从3.5到10.8.
- 基于的估计有所不同:横截面 (3.1-13.6),组内改善 (8.5-10.3),组内恶化 (3.1-6.3),组间改善 (9.1) 和组间恶化 (4.2).
- 对于总WISQOL分数的改善和恶化,确定了9个点的保守的MCID值.
结论:
- 在WISQOL得分的9个点的变化代表了结石患者的临床显著差异.
- 这一确定的门值可以帮助临床医生在解释WISQOL结果时做出决策.
- 这些发现增强了WISQOL问卷在临床实践和研究中的实用性.
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