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纳入软牙套内的抗菌剂的有效性:系统性审查

Olga Naka¹, Theodoros Tasopoulos², Frixos Frixou²

¹Department of Prosthodontics, School of Dentistry, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.

Materials (Basel, Switzerland)

|May 7, 2025

概括

添加到软假牙里面的抗菌剂有效地抑制了Candida albicans,改善了牙患者的舒适度. 虽然通常是安全的,但更高的度可能会影响内的机械性能.

科学领域:

牙科材料科学牙科材料科学
口腔微生物学口腔微生物学
牙修复牙修复牙修复牙修复牙修复

背景情况:

柔软的假牙增强了无牙患者的舒适性,但容易受到Candida albicans的殖民.
软中的Candida albicans可能会由于代谢和有毒副产品导致牙膏诱导的口腔炎.
需要有效的策略来防止微生物粘附和殖民于柔软假牙上.

研究的目的:

系统地审查软假牙内中结合的抗菌剂对Candida albicans的有效性.
评估这些剂对假牙内的物理和机械性能的影响.
为了确定常用的抗微生物药物及其有效性.

主要方法:

通过使用MEDLINE-Pubmed,EMBASE和Cochrane控制试验中心注册表进行了系统的文献审查.
与柔软假牙,抗菌剂和Candida albicans相关的关键词被使用,没有时间限制.
包括评估抑制作用和物质性质变化的研究.

主要成果:

许多研究表明,各种抗微生物剂被纳入软假牙内中,可以抑制Candida albicans的扩散.
抗微生物药物显示出显著的抗真菌作用,对物理性质的影响最小.
机械性质受到了与抗菌剂度相关的影响; nystatin 经常被确定.

结论:

将抗菌剂纳入软假牙内是一种成功的策略,可以抑制Candida albicans.
虽然有效,但抗微生物剂的度可以影响内的机械性能.
可能需要进一步的研究来优化剂的度,以获得最大的抗真菌效果和对材料性能最小的影响.

关键词:

在C. albicans中,它可以被发现.抗微生物剂是一种抗微生物剂.尼斯塔丁尼斯塔丁尼斯塔丁柔软的假牙内,可以用在牙上.

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