相关实验视频

Updated: May 12, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
13:00

Engineering Antiviral Agents via Surface Plasmon Resonance

Published on: June 14, 2022

2.2K

针对SARS-CoV-2 Spike-ACE2 相互作用的的计算设计和评估

Saja Almabhouh1, Erika Cecon2, Florence Basubas3

  • 1Structural Bioinformatics Laboratory (GRIB-IMIM), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain.

Molecules (Basel, Switzerland)
|May 7, 2025
PubMed
概括

一种新型,PEP10,有效地阻止SARS-CoV-2尖端蛋白与人类ACE2受体结合. 这种可以抑制病毒跨多个变体的进入,提供了一个有前途的治疗策略.

关键词:
在ACE2受体.这就是SARS-CoV-2病毒.分子动力学分子动力学质设计的设计.伪型的病毒颗粒.尖子蛋白质是什么?时间解析的FRET试验.

更多相关视频

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells06:39

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells

Published on: April 21, 2022

3.0K
A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation07:53

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation

Published on: January 9, 2019

33.1K

相关概念视频

Conjugated Proteins02:50

Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
18.1K
Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
12.4K