脑性麻儿童的免疫状态:越南的一项横截面医院研究
Thi Hong Hanh Khuc1,2, Tasneem Karim3,4,5,6, Minh Chau Cao2
1School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, Queensland, Australia.
PloS one
|May 7, 2025
概括
在越南,17.3%的脑性麻 (CP) 儿童没有完全接种疫苗,接种麻疹-红疹疫苗的比例较低. 诸如年龄较小和相关障碍等因素阻碍了这个脆弱群体接受疫苗接种.
科学领域:
- 儿科 儿科 儿科
- 公共卫生 公共卫生
- 神经学 神经学
背景情况:
- 脑 (CP) 影响儿童的发育和健康,需要全面的护理.
- 疫苗接种对于预防所有儿童的传染病至关重要,包括患有脑膜炎的儿童.
研究的目的:
- 评估越南脑 (CP) 儿童免疫覆盖率.
- 为了确定有助于该人口中不完全接种疫苗的特定因素.
主要方法:
- 在河内一家国家医院对765名CP儿童的潜在病例确定.
- 对越南扩大疫苗接种计划 (EPI) 时间表记录免疫史.
主要成果:
- 患有脑膜炎的儿童中有82.7%得到了充分的免疫,低于一般人口中的96.4%的免疫率.
- 不完全接种疫苗与年龄较小,家庭分娩,母亲教育水平较低以及CP和相关损伤的严重程度有关.
结论:
- 越南有很大一部分患有脑脊髓炎的儿童仍然没有足够的免疫,特别是对于麻疹-红疹.
- 需要有针对性的干预措施,以改善CP儿童获得疫苗接种和早期诊断的平等机会.
相关概念视频
01:25Immunodeficiency Diseases
833
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
833
01:51Vaccinations
43.0K
Overview
43.0K
01:22Development of Immunocompetence
238
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
238