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Updated: May 12, 2025

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DUX4激活了常见的和特定于环境的基因间转录和异型

Dongxu Zheng1, Anita van den Heuvel1, Judit Balog1

  • 1Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands.

Science advances
|May 7, 2025
PubMed
概括

DUX4基因的错误表达会导致面额骨骨缩症 (FSHD). 这项研究揭示了DUX4在胚胎和肌肉中的特定环境基因激活,影响了新的遗传基因位点,并推动了FSHD研究.

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