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Updated: May 12, 2025

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用于精确分析和治疗异质白血病的拼接调节动态

Meenakshi Venkatasubramanian1,2, Leya Schwartz3, Nandini Ramachandra3

  • 1Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

Science translational medicine
|May 7, 2025
PubMed
概括

连接失调,即使没有突变,驱动白血病亚型. 针对PRMT5和IRAK4等拼接调节器,为急性髓性白血病 (AML) 提供了一条新的治疗途径.

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