相关实验视频

Updated: May 12, 2025

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

针对可切除肺癌的免疫疗法

Colum Dennehy¹, Michael R Conroy¹, Patrick M Forde¹

¹Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

|May 7, 2025

概括

新辅助和外科期间的免疫疗法对早期肺癌有望,改善存活率并减少复发. 选择患者和管理副作用的挑战仍然是研究的关键领域.

科学领域:

在瘤学瘤学.
免疫学免疫学免疫学

背景情况:

肺癌是全球领先的健康问题.
免疫检查点封锁是高级和早期切除肺癌的标准治疗方法.

研究的目的:

审查肺癌中新辅助和外科期免疫治疗的现状和未来方向.
分析临床试验结果,安全概况以及对复发和生存的影响.

主要方法:

对可切除肺癌的新辅助和术后免疫疗法进行临床试验和现有文献的综述.
分析疗效,安全性,患者选择,治疗计划和手术影响.

主要成果:

新辅助和术后免疫疗法显示出早期疗效,并影响可切除肺癌的疾病复发和存活率.
关键的挑战包括优化患者选择,治疗时间,管理与免疫相关的不良事件和外科考虑.

结论:

免疫疗法为手术切除的肺癌提供了一个有前途的治疗策略.
需要进一步的研究来克服挑战,并建立最佳的新辅助和周围手术免疫治疗方案.

关键词:

一个辅助的辅助者.免疫检查点是一个检查点.免疫疗法免疫疗法局部化的局部化的局部化肺癌是一种肺癌.这是一种新辅助剂.非小细胞肺癌 (NSCLC) 是一种非小细胞肺癌.在外科手术期间的外科手术.可切除的可切除物手术手术手术手术手术手术手术

更多相关视频

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Published on: January 19, 2019

Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer

Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer

Published on: January 17, 2025

相关概念视频

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...