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Updated: May 12, 2025

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脂蛋白 (a) 在动脉样硬化心血管疾病中整合单细胞介导的血栓形成和炎症

Robert S Rosenson1, Ashley M Tate2, Olga G Grushko2

  • 1Metabolism and Lipids Program, Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, USA.

Journal of lipid research
|May 7, 2025
PubMed
概括

升高的脂蛋白 (a) [Lp(a) ]通过激活单细胞,放大动脉样硬化心血管疾病的风险. 这项研究揭示了Lp(a) 通过Toll-like受体2和NFκB信号触发炎症和血栓形成,突出显示了一种新的免疫血栓机制.

关键词:
炎症 炎症是一种炎症.脂蛋白 (a) 是一种蛋白质脂蛋白质是一种脂蛋白质.单细胞 (Monocytes) 是一种单细胞.血栓形成的原因是血栓形成.组织因子是组织因子.

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