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饮食炎症指数与中国产后抑郁症风险之间的关联

Guoquan Zhang¹, Hongyan Lin², Qinghan Ren³

¹Department of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China; Department of Infectious Disease Prevention and Control, Zhungeer Banner Disease Prevention and Control Center, Ordos 017100, China.

Journal of affective disorders

|May 7, 2025

概括

通过更高的饮食炎症指数 (DII) 表示的促炎症饮食与中国妇女产后抑郁症 (PPD) 风险增加有关. 采用抗炎饮食可能有助于减少PPD发病率.

科学领域:

营养流行病学营养流行病学
生殖健康生殖健康
精神病学是一个精神病学.

背景情况:

产后抑郁症 (PPD) 显著影响全球的母亲和婴儿福祉.
对于家庭和社会来说,PPD给家庭和社会带来了相当大的社会经济挑战.

研究的目的:

研究中国妇女的饮食炎症指数 (DII) 和PPD之间的关联.
探索炎症性细胞因子在DII-PPD关系中的调解作用.

主要方法:

2038名参与者使用自我评价抑郁症量表进行了PPD评估.
饮食炎症指数 (DII) 通过食物频率调查问卷计算.
使用倾向性得分匹配;对126个血液样本进行CRP,TNF-α,IL-1β和IL-6分析.
使用了后勤回归和引导调解分析.

主要成果:

36.4%的参与者表现出PPD症状.
较高的DII分数与增加的PPD风险相关 (T3与T1:OR=1.33,P<0.05).
较高的C-反应蛋白 (CRP) 水平与较高的PPD几率相关 (OR=1.34,P<0.05).
CRP调解了DII和PPD之间的关系.

结论:

较高的DII与中国妇女的PPD风险增加有关.
这些发现强调了抗炎饮食对于预防PPD的重要性.
建议限制促炎性食物摄入量以减少PPD风险.

关键词:

在C-反应性蛋白质中.饮食炎症指数饮食炎症指数调解调解是一种调解.产后抑郁症产后抑郁症

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