精神疾病与2型糖尿病患者中自杀风险之间的关联
Han-Sang Baek1, Kyu-Na Lee2, Dong Woo Kang3
1Division of Endocrinology and Metabolism, Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Gyeonggi-do, Republic of Korea.
Journal of affective disorders
|May 7, 2025
概括
患有精神障碍的糖尿病患者面临明显更高的自杀风险. 精神分裂症,双相情绪障碍,抑郁症,失眠和焦虑等疾病显著增加了自杀死亡风险.
科学领域:
- 内分泌学和精神病学 在
- 公共卫生研究 公共卫生研究
- 流行病学 流行病学
背景情况:
- 糖尿病是一种常见的慢性疾病,具有重大公共卫生影响.
- 伴随性精神健康状况越来越被认为是糖尿病管理中的复杂因素.
- 了解糖尿病,精神障碍和自杀风险之间的相互作用对于有针对性的干预至关重要.
研究的目的:
- 研究2型糖尿病患者中各种精神障碍与自杀死亡风险之间的关联.
- 在这个人群中量化与特定心理健康状况相关的自杀风险增加.
主要方法:
- 从韩国国家健康信息数据库中确定了875,671名患有2型糖尿病的成年人.
- 参与者从2009年至2021年进行了跟踪,以确定自杀死亡率 (ICD-10代码X60-X84).
- 多变量Cox比例危险模型被用来分析被诊断的精神障碍 (精神分裂症,双相情感障碍,抑郁症,焦虑症,失眠症) 和自杀风险之间的关系,调整为混因素.
主要成果:
- 在12.56年的中位数随访期间,发生了4755起自杀死亡.
- 任何精神障碍的存在都与增加全因死亡率有关.
- 经过调整的分析显示,自杀死亡风险显著增加:精神分裂症 (3.24倍),双相情感障碍 (2.47倍),抑郁症 (2.08倍),失眠 (2.03倍) 和焦虑 (1.63倍).
结论:
- 伴随性精神障碍是2型糖尿病患者中自杀死亡率的重要危险因素.
- 这些发现强调了糖尿病管理计划中综合心理健康护理的关键需求.
- 早期识别和治疗糖尿病患者的心理健康状况可能有助于减轻自杀风险.
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