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Updated: May 12, 2025

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由于有害的生殖系CHEK2变体,对造血性恶性瘤的倾向

Ryan J Stubbins1,2, Stephen Arnovitz3, Jennie Vagher4

  • 1Leukemia/BMT Program of BC, BC Cancer, 2775 Laurel Street, V5Z 1M9, Vancouver, BC, Canada.

Leukemia
|May 7, 2025
PubMed
概括

生殖系CHEK2变异,特别是p.I157T,与遗传性造血性恶性瘤 (HMs) 有关. 这些变异增加了患髓性和淋巴性白血病的风险,影响了患者的生存率.

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